During the changing relations between mutants and the city of New Orleans, two of the best guns for hire come to town with a mission in mind, and their target for that mission is an X-MAN!

DEADPOOL and OUTLAW guest-star in this dangerous tale of MAYHEM vs. MUTANT! Also, an Outlier gets ARRESTED? Nightcrawler gets the wrong BEER? All this and more in our wildest issue yet!